OpenEvidence, the ‘ChatGPT for doctors,’ raises $250m at $12B valuation, 12x from $1b last Feb

**OpenEvidence** raised **$12 billion**, a 12x increase from last year, with usage by 40% of U.S. physicians and over $100 million in annual revenue. **Anthropic** released a new **Claude** model constitution under **CC0 1.0**, framing it as a living document for alignment and training. **Podium** reported over **$100 million ARR** from **10,000+ AI agents**, shifting from software sales to AI operators. Innovations in agent memory and reliability include the **Agent Cognitive Compressor (ACC)** and multi-agent scientific workflows via **MCP-SIM**. Agentic benchmarking shows challenges in long-horizon tasks with models like **Gemini 3 Flash High**, **GPT-5.2 High**, and **Claude Opus 4.5 High** scoring modestly on professional services and legal research benchmarks.